Commentary on the Tosefta, Toldot Yitzchak, by Rav Yitzchak Itzik Halevi ben Shlomo Zalman of Lemgau, written in Amsterdam and Groningen 1776-1800.
תולדות יצחק מאירת עינים, פירוש על התוספתא מאת הרב יצחק איצק הלוי בן שלמה זלמן מלעמגא
University of Amsterdam Library, Bibliotheca Rosenthaliana, Manuscript #2.
The commentary covers the following Masechtot: Shabbat, Eruvin, Pesachim, Betzah, Rosh Hashanah, Yoma, Megillah, Shekalim, Yevamot, Ketubot, Kiddushin, Gittin, Nedarim, Nazir, Sotah, Bava Kamma, Bava Metzia, Bava Batra, Avodah Zarah, Sanhedrin, Shavuot, Makkot, Eduyot, Horayot, Zevachim, Menachot, Chulin, Keritot, and Mikvaot.
The author was chief rabbi of Groningen until his death in 1801. His cousin, Yitzchak ben Mordechai tried to have the work printed. He published a broad sheet with proofs from the manuscript in 1801, to propagate the work and attract subscribers, but without results. In 1809 the author’s pupil Rav Avraham Prins tried it again and reprinted the broad sheet at the end of his work, Likkutei Tzvi, Amsterdam, 1809, but again in vain. Currently majority of the work remains in manuscript. Chapter 3 of Yoma was published in Journal Yeshurun, Volume 9, pp. 76-91 and can be downloaded here. The commentary on Masechta Megillah was published by Machon Ofek in 2001 with notes by R’ Avraham Shoshana.